Milk Thistle and its Therapeutic Potential in Liver Disorders: A Comprehensive Review
Abstract
Liver disorders need effective treatments to enhance function, reduce inflammation, and prevent viral disorders. Silymarin shows promise, but its optimal dosage and duration remain unclear, complicating standardized clinical use. Milk thistle [Silybum marianum (L.) Gaertn.] and its active component, Silymarin, has shown its effectiveness in enhancing liver function, mitigating inflammation, and preventing further damage in conditions from alcoholic fatty liver, non-alcoholic fatty, drug-induced liver injury and viral hepatitis. Clinical trials have furnished evidence of silymarin's beneficial effects on liver health, particularly in conditions like cirrhosis. However, it's crucial to acknowledge that while silymarin appears to possess hepatoprotective properties, its optimal dosage and duration of use may vary depending on the specific liver condition. Understanding the therapeutic role of silymarin within the intricate landscape of liver illnesses can contribute to more effective strategies for patient care and improved outcomes.
Keywords: Milk thistle; Silybum Marianum; Liver disorders; Clinical trials; Oxidative stress
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